Regency Specialist Hospital +6017 523 3183
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Singapore Mount Alvernia Hospital +65 9727 3900
Medical Centre A, #02-03, 820 Thomson Road Singapore 574623
Kidney Tumour

What is a Kidney Tumour?

A kidney tumour refers to an abnormal mass of tissue in the kidney, which can either be benign (non-cancerous) or malignant (cancerous). While Renal Cell Carcinoma (RCC) is the most common form of malignant kidney cancer in adults, benign kidney tumours are also prevalent and often less dangerous. Benign tumours do not spread to other organs or tissues, but they may still require medical attention if they cause symptoms or impair kidney function.
Kidney Tumour Singapore
A kidney tumour can either be benign or progress into kidney cancer, requiring medical evaluation for proper diagnosis.
There are several types of benign kidney tumours that can form in the kidneys. These include:

Renal Oncocytoma

This is the most common type of benign kidney tumour, accounting for about 3-7% of all kidney masses. While these tumours can grow large, they generally do not metastasize. However, they can sometimes be difficult to distinguish from RCC based on imaging alone, which makes biopsy or surgical removal necessary for a definitive diagnosis​.

Angiomyolipoma (AML)

A benign tumour made up of blood vessels, muscle, and fat, angiomyolipomas are often associated with a genetic disorder called tuberous sclerosis, though they can also occur sporadically. Large AMLs pose a risk of bleeding, and depending on their size and symptoms, treatment may be necessary​.

Fibroma

These are rare benign tumours composed of fibrous tissue. Though they are usually small and asymptomatic, they may require monitoring to ensure they do not interfere with kidney function.

Lipoma

composed of fat cells, lipomas are also a rare type of benign kidney tumour. Similar to fibromas, these tumours are typically small and may not cause symptoms, but larger lipomas might require intervention if they grow or cause discomfort.

In Singapore, the incidence of kidney tumours has been on the rise in recent years, reflecting trends seen globally. According to the Singapore Cancer Registry, RCC is more common among men than women, particularly in those aged 50 and above.

What causes Kidney Tumours?

Kidney tumours develop when the cells within the kidney undergo abnormal changes in their DNA, leading to uncontrolled growth. This disruption in the cellular DNA affects the normal regulatory functions that manage cell division and death, causing the formation of a mass, or tumour. In healthy cells, DNA instructs cells to grow, divide, and eventually die when appropriate.
However, in kidney tumours, the altered DNA causes cells to multiply rapidly and avoid normal cell death. This leads to the accumulation of excess cells, forming either benign or malignant tumours depending on whether they invade nearby tissues or spread to other parts of the body.
While the exact cause of these DNA mutations is often unclear, certain molecular changes, such as mutations in the VHL gene (commonly associated with renal cell carcinoma), can play a significant role. Additionally, benign tumours like angiomyolipomas are often linked to inherited genetic conditions, such as tuberous sclerosis complex. The cause of these mutations may be spontaneous or hereditary, and they trigger the uncontrolled growth characteristic of kidney tumours.

What are the symptoms of Kidney Tumours?

Kidney tumours often do not present symptoms in their early stages, which makes them difficult to detect without imaging tests. However, as the tumour grows, patients may begin to experience noticeable signs. Common symptoms of kidney tumours include:

  • Blood in the urine (hematuria), which may appear pink, red, or cola-coloured
  • Persistent pain in the side or lower back
  • A palpable lump in the abdomen or lower back
  • Unexplained weight loss
  • Fatigue
  • Fever that is not related to an infection

If any of these symptoms occur, it is important to seek medical advice for further evaluation and diagnosis.

Kidney Tumour Symptoms Singapore
A common symptom of a kidney tumour is haematuria, or blood in the urine, which may indicate the presence of a tumour.

Who is at risk of Kidney Tumour in Singapore?

In Singapore, certain groups of individuals are at higher risk of developing kidney tumours, including both benign and malignant forms. Risk factors include lifestyle habits, underlying health conditions, and genetic predispositions that increase the likelihood of tumour development. Key risk factors for kidney tumours include:

By understanding these risk factors, individuals in Singapore can be more aware of the steps they can take to reduce their risk and seek early medical intervention if needed.

Age

The risk increases with age, particularly after the age of 50, with most diagnoses occurring between 55 and 74​.

Smoking

Smoking is a major contributor, as it significantly increases the chances of kidney tumours by causing harmful changes in kidney cells​.

Obesity

Individuals with obesity are at greater risk, likely due to the hormonal and metabolic changes that accompany excess body fat​.

High blood pressure

Hypertension, or high blood pressure, has been linked to an increased risk of kidney tumours, although the exact mechanisms are not fully understood​.

Family history

A family history of kidney tumours or certain genetic conditions, such as von Hippel-Lindau disease, can increase the likelihood of developing kidney tumours​.

Chronic kidney disease or dialysis

Patients with advanced kidney disease or those who have undergone long-term dialysis have a higher incidence of kidney tumour.

How is a Kidney Tumour diagnosed?

At Allen Sim Urology, we understand how crucial early and accurate diagnosis is for the effective treatment of kidney tumours. That’s why we employ a comprehensive range of diagnostic tools and techniques to ensure we get a clear understanding of each patient’s condition. Our approach to diagnosing kidney tumours typically involves the following methods:

We begin with non-invasive imaging tests, such as ultrasound, CT scans, or MRI, to get detailed images of the kidneys. These tests help us identify the presence, size, and location of any tumour within the kidney​.

Urinalysis can detect blood in the urine, which is a common early sign of kidney tumours. This simple test can provide critical early clues​.

Blood work allows us to check for markers of kidney function, such as creatinine levels, and signs of anaemia, which may indicate a tumour. Elevated liver enzymes might also suggest that the tumour has spread​.

In cases where imaging does not clearly indicate whether a tumour is benign or malignant, a needle biopsy may be performed. A small sample of the tumour tissue is removed and analysed under a microscope to confirm the diagnosis​.

At Allen Sim Urology our healthcare experts, take the time to thoroughly review these diagnostic results with each patient, and ensure they understand their condition and are informed about the next steps in their treatment journey.

What are the treatment options for Kidney Tumours in Singapore?

At Allen Sim Urology, we believe in providing personalised and comprehensive care when it comes to treating kidney tumours. Each patient’s treatment plan is tailored based on the type, stage, and size of the tumour, as well as their overall health. We offer a variety of treatment options, from minimally invasive techniques to more complex surgeries, to ensure the best possible outcomes. Here are the treatment options we commonly provide:

Monitoring

For small, slow-growing tumours, especially in older patients or those with multiple health issues, we may recommend closely monitoring the tumour with regular imaging. This approach helps avoid unnecessary treatment while keeping a close eye on any changes​.

Surgery

Surgery is often the first-line treatment for kidney tumours. At Allen Sim Urology, we offer both partial nephrectomy (removal of the tumour while preserving kidney function) and radical nephrectomy (complete removal of the kidney if the tumour is larger or more aggressive). We use minimally invasive techniques such as laparoscopic and robotic-assisted surgery whenever possible to minimise recovery time and discomfort​.

Ablation therapies

For small tumours, we offer cryotherapy (freezing the tumour) and radiofrequency ablation (using heat to destroy the tumour). These non-surgical techniques are ideal for patients who may not be suitable candidates for surgery due to age or other health concerns​.

Immunotherapy & Targeted Therapy

For more advanced or metastatic kidney tumours, we utilise modern systemic therapies, including immunotherapy and targeted therapy. These treatments help harness the body’s immune system or target specific cancer cell pathways to slow the growth or spread of the tumour​.
At Allen Sim Urology, our team is dedicated to guiding each patient through the treatment process, ensuring they feel informed and supported every step of the way.
If you’re experiencing any symptoms or have concerns about kidney tumours, schedule an appointment with Allen Sim Urology today for expert diagnosis and personalised treatment options.

Frequently Asked Questions (FAQs)

Yes, not all kidney tumours are cancerous. Benign tumours like angiomyolipomas and renal oncocytomas are non-cancerous and generally do not spread to other parts of the body. However, depending on their size and location, they may still require treatment to prevent complications.

No, not all kidney tumours require surgery. Small, benign tumours may be monitored constantly, especially if they are not causing symptoms or growing. Treatment options are determined based on the size, type, and behaviour of the tumour.

The growth rate of kidney tumours varies. Some, like small renal masses, can grow very slowly and might not require immediate treatment. Others, particularly malignant tumours, may grow faster and spread to other parts of the body, requiring prompt intervention.

If malignant, kidney tumours can spread to nearby tissues and distant organs, a process known as metastasis. Common areas where kidney cancer may spread include the lungs, bones, and liver.

Recovery time depends on the type of surgery. Minimally invasive procedures like laparoscopic or robotic-assisted surgery generally have shorter recovery times, usually around 2-4 weeks, while traditional open surgeries may require longer recovery periods.